The research behind CARE for MDD
CARE for MDD was developed with the principles of harnessing the brain’s natural ability to change and adapt.
Exercises are designed to strengthen the connections between parts of the brain involved in cognitive control (thinking) and emotional processing (feeling). The aim of the exercises is to improve control of emotional processing, helping to break the cycle of negative thinking.
The brain exercises have been trialled with patients experiencing major depressive disorder (MDD, also known as depressive disorder or clinical depression) and these studies have indicated a benefit in reducing depressive symptoms.1-3
Patients who performed the brain exercises consistently showed improvements in:2
Ability to perform work and day-to-day activities
Rumination, or focussing on negative thoughts
AnxietyA study indicates that, changes in symptoms of depressive disorder were also consistent with changes in connections between the cognitive and emotional processing parts of the brain.4
Further information
If you have further questions or would like to learn more about CARE for MDD you can check our FAQs or contact us below:
Useful resources
A range of resources are available to you to help navigate the CARE for MDD app, which include:
Please download the Instructions for use for a detailed description of key features of the CARE for MDD app
Please download the Patient user guide to learn about how the app works and how to access the exercises
Please download the Patient visual guide for a one-page overview of what to expect from the CARE for MDD appAbbreviations
- MDD: Major Depressive Disorder
References
- 1. Iacoviello BM et al. Depress Anxiety 2014;31:699–706
- 2. Iacoviello BM et al. NPJ Digit Med 2018;1:21
- 3. U.S. Food and Drug Administration. Marketing Authorisation for REJOYN (known as CARE for MDD in Great Britain). Available at: www.accessdata.fda.gov/cdrh_docs/pdf23/K231209.pdf (accessed May 2024)
- 4. Hoch MM et al. Chronic Stress 2019;3:1–10
